Desquamation
Definition
Desquamation is the natural, ongoing process by which the outermost layer of dead skin cells (corneocytes) sheds from the skin's surface. Under normal conditions, this process is invisible — skin cells are produced at the base of the epidermis, gradually migrate to the surface over about 28 days, die, and quietly slough off. However, when desquamation is disrupted — due to dryness, certain skin conditions, or environmental factors — visible flaking, peeling, or scaling can occur. Conditions like psoriasis involve abnormally accelerated cell turnover, leading to excessive desquamation. Exfoliating ingredients like AHAs and retinoids work by promoting more even, controlled desquamation. Proper hydration and moisturization support healthy desquamation by maintaining the enzymes that break down the bonds between dead skin cells.
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